Enzo Fernandez is a doubt for the Christmas Eve trip to Wolves after being pictured in tears following Chelsea's win over Newcastle in the Carabao Cup.
The 22-year-old midfielder was substituted in the 32nd minute and stayed in the dressing room for most of the match, before re-emerging just as Chelsea reached the semi-finals of the League Cup via a penalty shootout.
Mauricio Pochettino revealed post-game that the midfielder had been suffering from illness and asked to be substituted, amid rumours come out of Argentina that he is suffering from a more serious groin injury.
The Blues are already contending with a sizeable absentee list. Carney Chukwuemeka, Trevoh Chalobah, Ben Chilwell, Marc Cucurella, Robert Sanchez, Reece James, Wesley Fofana, Lesley Ugochukwu and Romeo Lavia will likely be out.
Christopher Nkunku is ready after making his debut in midweek, scoring one of four penalties in the shootout and playing 20 minutes as Chelsea chased their equaliser at Stamford Bridge.
Mykhailo Mudryk ultimately scored a 92nd-minute leveller and could now return to the starting line-up.
Penalty hero Djordje Petrovic will continue as the goalkeeper, with Thiago Silva potentially to be rested to herald Malo Gusto's return after he excelled from the bench in midweek.
Gusto could slot in at right-back alongside Axel Disasi, Benoit Badiashile and Levi Colwill in defence.
Moises Caicedo and Conor Gallagher will continue in midfield, with Palmer filling in for Fernandez. Mudryk should join Raheem Sterling and Nicolas Jackson in an attacking front three.
Predicted Chelsea XI: Petrovic; Gusto, Disasi, Badiashile, Colwill; Caicedo, Gallagher; Sterling, Palmer, Mudryk; Jackson
Doubts: Fernandez, Lavia
Injuries: Chukwuemeka, Chalobah, Chilwell, Cucurella, Sanchez, James, Fofana, Ugochukwu
Time and date: 1pm GMT on Sunday December 24, 2023
Venue: Molineux
TV channel: Sky Sports