European teams have enjoyed more than a decade of success since Brazil's Corinthians became the last side from outside the continent to claim the title.
City hope to become the fourth English team to be named world champions, after Chelsea's triumph two years ago added to Liverpool and Manchester United's titles.
They will have to do so without Erling Haaland, against a Fluminense team spearheaded by veteran striker German Cano.
Where to watch Fluminense vs Man City
TV channel: In the UK, the final will be televised live on TNT Sports 2, with coverage beginning at 5:45pm GMT before a 6pm kick-off.
Live stream: Subscribers can also catch the contest live online via the Discovery+ app and website.
Live blog: You can follow all the action on matchday via Standard Sport’s live blog.